Clinical meaningfulness of the CDR-SB, FAQ and MMSE: A study to establish
progressor definitions using the National Alzheimer's Coordinating Center 
   Lead Investigator:    Spyridon Roumpanis
   Institution      :    F.Hoffmann - La Roche Ltd
   E-Mail           :    spyros.roumpanis@roche.com
   Proposal ID      :    1239



   Proposal Description:
   The main research question for this study is to determine the progressor definitions for selected endpoints, including the CDR-SB, MMSE and FAQ, in patients with prodromal, mild and moderate AD from the National Alzheimer?s Coordinating Center (NACC) database. The outcome of interest include the longitudinal changes of the CDR-SB, MMSE and FAQ.